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Weight Loss Drugs, Safe or Fatal?

Weight Loss Drugs, Safe or Fatal?

Ordering Clenbuterol online? Maybe you should check out this first?!

Are you thinking about ordering Clenbuterol online?

Most of the insufficiently persistent fighters on the path of “reduction of fat deposits” often come to the famous question – WHAT TO TAKE TO BURN AN UNWORTHY FAT QUICKLY AND EFFICIENTLY?

Many start with the strongest fat burners from the category of complex burners. However, they are “filled” with numerous stimulants such as caffeine, synephrine, catechin from green tea, etc.

Of course, the effects are often not in line with the bombastic advertising slogans for the mentioned supplements, so there is no satisfaction.

Then begins the “inquiry from more experienced exercisers,” searching the Internet to find the ideal solution. Finally, they come to the “dark side of the Force” – Clenbuterol, salbutamol, ephedrine, T3, and sibutramine, to name a few.

Let’s immediately, in the beginning, distance ourselves from the desire to advertise the mentioned “banned substances”! Instead, our goal today will be to point out all possible side effects and risks of abusing these substances.

So, the prince of fat burners itself – CLENBUTEROL (aka. Clen)

What is Clenbuterol?

Clenbuterol is a compound that belongs to a class of drugs called beta2-agonists. Medicines in this category can cause dilation of the bronchial muscles.

Beta2-agonists are often used to treat asthma. And they are approved in the United States for veterinary use in non-food animals.

It has been used for decades to treat chronic obstructive pulmonary disease (COPD), which consists of chronic bronchitis and emphysema. Thus, “clen” is a sympathomimetic that binds predominantly to beta-2 receptors, primarily found in the heart and smooth muscle tissue (lungs, blood vessels, uterus, digestive tract, eye).

I’m telling you this to see how deep this ‘you-think-supplement’ can reach inside of you.

Of course, there are also effects on skeletal muscles and the pancreas and kidneys.

In addition to being used to treat asthma, Clenbuterol has become popular as a weight-loss supplement. That’s because of its effect on muscle growth and fat reduction.

And you can buy Clenbuterol online in powder or liquid form.

What do most people have on their minds when ordering Clenbuterol online?

The most crucial cause of Clenbuterol abuse is the side effect of the same – THERMOGENESIS.

It ” activates ” cellular organelles- mitochondria through a series of cascading reactions after Clenbuterol binds to the beta-2 receptor.

Then they generate heat from free fatty acids as fuel when entering the target cell. Thus, the effect of beta-2 stimulation is to accelerate basal metabolism.

Unlike e.g., ephedrine, Clenbuterol has no direct effect on adipose tissue cells but, by indirect mechanisms, leads to the mobilization of “fat depots in our body.”

Of course, all this sudden stimulation is not so harmless. In addition to “strong” binding to beta-2 receptors, Clenbuterol also binds to beta-1 receptors, leading to high blood pressure.

Also, beta-1 stimulation can lead to vasoconstriction – blood vessels of the heart and brain … So headaches are common.

And you can expect that due to the long “half-life of the drug” – 24-48 hours, side effects are difficult to control!

Steroids to lose fat fast is not a way to go because of these

Insomnia, irritability, nervousness, unpleasant sweating with minimal effort… to name a few minor issues.

We could say that is the starting price of Clenbuterol.

A big problem, in the beginning, is the “tremor of the hands” – trembling hands, sometimes literally the feeling of shaking, which is a consequence of “sustained neuromuscular junction.” Anecdotally said, as soon as there is no tremor of the hands, clen does not work, and you must increase the dose.

A 30-year-old male presented with tremors and tinnitus and complains of feeling “shaky and fluttery” after ingesting 3000 μg of Clenbuterol (15 mL of 200 μg/mL syrup). He reported obtaining clenbuterol “over-the-counter” for weight loss. (1)

Another major problem is cramps (muscle cramps), often associated with the resulting “mild” hypokalemia and a drastic decline in taurine in the heart and skeletal muscle.

They represent the third and most significant problem: HEART ARRHYTHMIA.

Users of “clen” often mention skipping the heart, “heartbeat in peace.”

In like manner, sometimes more severe problems can arise (irritation of the heart’s conduction system). Relevant research shows that too frequent, continuous (mis) use can lead to scarring changes in the heart muscle.

The possibility of complicating glaucoma (increased intraocular pressure) is also something you should know.

There are claims based on animal research on “clen” that it also has an anabolic effect (increases muscle mass), but such claims have not been proven by research in humans.

Earlier, Clenbuterol was used for breeding pigs and cattle to increase the “share of pure meat.”

Owners and vets also gave it to racehorses!

A big problem here is the down-regulation of beta-2 receptors (reduces the number and sensitivity of receptors), so there are special intake schemes to maintain the effectiveness of “clen” – 3 days on, 2 days off, or 14 days on (with a gradual increase in dose), then 14 days off…

To omit this, some even take ketotifen (an antihistamine) to restore receptor sensitivity without the need to “take off the clen.”

So, yes, Clenbuterol certainly “works,” but at what price?!

What can you get when ordering Clenbuterol online?

In a few months, thirteen cases of Clenbuterol were located at the two regional poison centers. They all had between was 25 and 29 years.

Eleven patients (85%) were male. The ingested dose ranged from 300 to 4500 μg (mean = 2600 μg). The single child patient ingested his mother’s Clenbuterol, who had obtained the drug via the Internet for weight loss.

Eight patients got help and were released from the emergency department, with three patients admitted to the hospital, and 2 had more health complications. Almost all of them purchased Clenbuterol via the Internet for “bodybuilding” or “weight loss.”

An unintentional exposure occurred in one patient (a 46-year-old veterinary worker) (75 μg/mL) while working.

From January 2007 through November 2012, a total of 426 human Clenbuterol cases were reported to NPDS. (2)

Is honey healthy for weight loss?

Some people will say that honey contains sugar which is a source of “empty calories,” which means no health use in consuming it.

However, unlike refined sugar, honey also contains valuable minerals.

These vitamins and minerals are used to digest sugar, so many essential nutrients are used. Nutrients are also necessary for dissolving fats and cholesterol. Therefore, when you overeat refined sugar, you tend to gain weight not only because of calories but also because of the later lack of vitamins and minerals.

Honey balances this effect because it is a good source of nutrients that help people achieve weight loss if consumed in limited quantities.

Honey provides water, energy, fiber, sugar, vitamins, and minerals. In addition, it contains iron, sodium, potassium, phosphorus, zinc, and calcium.

It also includes folate, niacin, riboflavin, vitamin C, and vitamin B6 but has low selenium, protein, fiber, and some amino acids.

In overweight or obese people, honey not only reduces the risk of cardiovascular disorders but also does not increase body weight. In addition, research shows that consuming honey can help lower cholesterol levels compared to sugar. It also leads to a lower increase in plasma glucose levels than sugar.

DOES MANUKA HONEY HELP WITH WEIGHT LOSS? (THE MECHANISM OF MANUKA HONEY IN REVERSING METABOLIC SYNDROME)

Metabolic syndrome is a constellation of four risk factors: central obesity, hyperglycemia, dyslipidemia, and hypertension, which predispose a person to cardiometabolic diseases.

Many studies reported the beneficial effects of honey in reversing metabolic syndrome through its antiobesity actions, including this one I’m about to share with you. (3)

Given the role of inflammation and oxidative stress in the development of metabolic syndrome, honey could prevent metabolic syndrome with the capacity to quench these processes.

The therapeutic effects of honey on obesity largely depend on the antioxidant and anti-inflammatory properties of its polyphenol and flavonoid content.

Manuka honey has the highest content of polyphenols, with 899.09 ± 11.75 mg gallic acid/kg (5)

Polyphenols and flavonoids are potent antioxidants because they can donate hydrogen to scavenge free radicals in oxidative stress.

For example, quercetin, caffeic acid (CA), and chlorogenic acid are polyphenols that possess iron-chelating and iron-stabilizing properties, preventing free radical formation.

Furthermore, polyphenols, such as apigenin, quercetin, and kaempferol, may also exert their anti-inflammatory properties by modulation of enzymes involved in proinflammatory activities.

And that means that these bioactive compounds may contribute synergistically to the antimetabolic effects of honey.

Or, in plain English…help you lose that extra fat.

So, how Manuka honey does it?

Several studies have linked obesity with mitochondrial alterations. This is because the excessive intake of nutrients provokes the mitochondria to become overloaded with fatty acids and glucose.

Then oxidative stress triggers obesity by stimulating white adipose tissue (WAT) deposition and altering food intake. (6)

Manuka honey prevents oxidative damage and preserves mitochondrial functionality via activating the AMPK/Nrf2 signaling pathway.

It also reduces lipid accumulation from 33.78% to 70.36%.

But in the end, the primary approach stays as a general rule.

Lifestyle changes continue to be the head approach in treating metabolic syndrome.

Meanwhile, caffeic acid and quercetin in manuka honey are also known to reduce body weight and fat mass. In addition, fructo-oligosaccharides in honey are also known to alter lipid metabolism by lowering FAS activity.

And that means improved glucose tolerance, decreased fat mass, and more success in the bodybuilding arena.

One example of how you can use manuka honey to lose fat

You only need to take one to two spoons of honey! This approach is called the “hibernation diet.”

The critical rule of the hibernation diet is to take one to two spoons of honey before going to bed, either with warm water, in a smoothie, or directly from a jar.

The diet was devised by British pharmacist and nutritionist Mike McKinnis, who says that honey simultaneously works for better sleep and weight loss simply by using the biology of our body and cooperating with it instead of working against it.

One aspect of the hibernation diet, due to weight loss, is consuming a spoonful (5 g) of honey before bedtime. While you sleep, honey will continue to stimulate the liver and alleviate many stress hormones in your system.

As the name suggests, it helps you sleep healthy and relaxed.

The hibernation diet works by activating the body’s natural weight-controlling mechanism.

“You don’t have to fight against your body every step of the way to achieve a healthy weight,”– says McKinnis.

The key is to help restore the body’s regenerative mechanisms during the night, speeding up metabolic processes and fat burning and alleviating stress hormones’ effects. Thus helping yourself sleep and look better.

In the end …

Let’s always start from the fact that the priority is a balanced diet (reasonable restriction in diet) and a well-formulated training plan to reduce fat deposits successfully.

They are all we need to succeed in this field.

Fat burners from “this or that side of the law” ARE NOT AND WILL NEVER BE THE MAIN MEANS OF PROGRESS IN THE REDUCTION OF FAT DEPOSITS!

All in all, we can see that Clenbuterol is not a naive substance at all, with too many side effects that are sometimes very difficult to control.

“Clen” is not a shortcut!

We eat healthily 365 days a year, exercise regularly, discipline ourselves a little bit, and we will never have problems with fat deposits or health for that matter.!

And if you understood the story above, you should also know that Clenbuterol is no longer used in modern medicine (pharma dinosaur)!

Think again about ordering Clenbuterol online…

ORIGINALLY PUBLISHED on blog.manukanatural.com

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